The Defense Health Agency is seeking proposals for funding in support of the research areas listed below.
Depending on the type of funding mechanism used, projects may be up to 5 years in length.
Clinical trials are allowed.
Pre-proposals/pre-applications are mandatory and will be accepted and assessed on a rolling basis until 30 September 2027.
Research Areas of Interest
- Military Infectious Diseases – R&D of solutions for the prevention, treatment, and diagnosis of infectious diseases. Solutions can include materiel products as well as knowledge product research to advance clinical practice guidelines to address nominated diseases. Solutions should minimize the infectious disease threat to the Joint Force, maintain readiness, and preserve operational effectiveness. Specifically, MID intends to fund studies to develop preclinical safety and efficacy data to file an IND with the FDA to support first in human studies. For solutions at a higher level of maturity, MID intends to fund activities to execute phase 1 and/or 2a clinical studies, including cGMP manufacturing if required, to advance the product.
- Combat Casualty Care – R&D of products to stop blood loss, resuscitate the casualty and limit the immediate, short- and long-term deleterious consequences of severe haemorrhage. Development and translation into clinical practice of effective management of forward resuscitative measures to include burn at PON through the continuum of care. Identify and develop new and/or improve existing solutions for severe haemorrhage at PON. Develop solutions to provide prolonged care and stabilisation of complex wounds or burns. Identify, develop and evaluate solutions to treat combined and complex injuries (eg ballistic, blast, blunt and burn). Develop solutions to optimise clinical capabilities during transport.
- Traumatic Brain Injury – R&D of solutions for the diagnosis, treatment, and prevention of further brain injuries. Solutions can include materiel products as well as knowledge product research to advance clinical practice to address the nominated concerns. Solutions should minimize the brain injury threat to the total force, maintain readiness, and preserve operational effectiveness.
- Psychological Health – Research to enable rapid psychological return to duty, during operations and in garrison. Research to develop an integrated ecosystem of solutions, for use by medical assets across all environments, to rapidly identify individuals at risk for or experiencing psychological distress symptoms that put the mission at risk.
- Sensory Systems – Pain treatment; ocular injury stabilisation; auditory injury assessment; ocular injury assessment.
- Musculoskeletal Injury – point of care decision support tools; injury risk mitigation; enhance acute MSKI care for optimised outcomes; enhance pre-hospital capability and capacity of MSKI; return to duty support tools; intraosseous antibiotics for osseointegration; optimise human performance for injury prevention.
- Environmental Exposures – countering health threats, disease and non-battle injury through prevention, assessment and treatment across a wide range of military relevant environmental exposures.
- Directed Energy/Radiation Health – adding clarity to discriminators in which bioeffects become health effects following radiofrequency, optical or acoustic exposures in an operational environment. development of medical countermeasures to counter acute radiation exposure.
- DoD Working Dogs – development of health readiness solutions for canine injury prevention, wound recovery, therapeutics, and pain management emphasizing return to duty. Research leads to solutions for acute and chronic MSKI prevention, diagnosis, and treatment.
Document
BAA – Extramural Medical Research – HT942523SBAA1_09Jul2025
