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US Dept of Defense – Bone Marrow Failure Research Program

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US Dept of Defense – Bone Marrow Failure Research Program


Idea Development AwardHT942524BMFRPIDA 

  • up to USD$530,000 over 3 years
  • pre-proposals due 17 July 2024
  • supports innovative ideas and high-impact approaches based on scientifically sound evidence to move toward the vision to understand and cure bone marrow failure diseases
  • must address at least one Focus Area
  • may include relevant preliminary data
  • clinical trials not allowed
  • hypothesis-driven correlative studies associated with clinical trials that meet the innovative intent are encouraged
  • Document – Funding Opportunity: HT942524BMFRPIDA_GG


Investigator-Initiated Research AwardHT942524BMFRPIIRA

  • up to USD$675,000 over 3 years (funding level 1) or
  • up to USD$850,000 over 2 years (funding level 2 – new drug-enabling efforts
  • pre-proposals due 17 July 2024
  • Funding level 1 – supports studies that further develop mature ideas, expand upon key discoveries and have potential to make significant advances
  • Funding level 2 – supports investigational new drug-enabling efforts which should be empirical in nature, product driven and focused on the accumulation of data to support an IND application to the FDA
  • emphasis on research and impact
  • preliminary data required
  • clinical trials not allowed
  • must address at least one Focus Area
  • Document – Funding Opportunity: HT942524BMFRPIIRA_GG


Focus Areas

  • understand the causes and progression of BMF diseases
  • find effective BMF treatments and cures

Relevant diseases include but are not limited to: aplastic anemia; Diamond-Blackfin anemia; dyskeratosis congenita/telomere biology disorders; Fanconi anemia; GATA2 deficiency; induced BMF – radiation/chemical; myelodysplastic syndromes; paroxysmal nocturnal heoglobinuria; Pearson’s disease; SAMD9/SAMD9L germline mutations; severe congenital neutropenia; Schawchman-Diamond syndrome; VEXAS sysndrome


Apply here



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