Idea Award – HT9425-23-LRP-IA
- up to USD$300,000 over 2 years
- pre-proposals due 20 July 2023
- Supports innovative, high-risk/high-reward research that could ultimately lead to a critical discovery or major advancement relevant to lupus.
- Emphasis on innovation.
- must address one of the FY23 Focus Areas
- clinical trials not allowed
- preliminary data not required
Impact Award – HT9425-23-LRP-IPA
- up to USD$1M over 4 years
- pre-proposals due 20 July 2023
- Supports high-risk/high-reward research which, if successfully addressed, has the potential to make a major impact in lupus research.
- Emphasis on impact
- must address one of the FY23 Focus Areas
- clinical trials not allowed
- preliminary data encouraged but not required
Transformative Vision Award – HT9425-23-LRP-TVA
- up to USD$2.5M over 4 years
- pre-proposals due 20 July 2023
- Supports research that will have an intervention at the individual and/or health care system level, which will result in near-term impact on the health-related quality of life of persons living with lupus.
- Emphasis on near-term impact to quality of life.
- research team must include one or more Consumer Advocates
- must address one of the FY23 Focus Areas
- animal trials not allowed
- preliminary data required
FY23 Focus Areas
- Understanding how lupus disease heterogeneity impacts risk of disease, disease presentation, clinical course, and outcomes; using a diverse range of research disciplines including, but not limited to, biopsychosocial studies, personalized medicine, variation in treatment studies, health economics, socioeconomic studies, environmental studies, systems biology, maternal fetal health, and epidemiological studies
- Understanding the biological mechanisms of lupus disease including, but not limited to, studies of informative/rare patients
- Determining the pathobiology of end organ injury related to lupus disease in target human tissues
- Improving quality of life for individuals living with lupus including, but not limited to, addressing social determinants of health, access to health care resources, outcomes research, patient-reported outcomes, symptom and disease control, comparative effectiveness research, maternal fetal health and issues and challenges that, when addressed, make day-to-day living with lupus easier and life more fulfilling
- Understanding the underlying genetic and epigenetic components and gene – environment interactions of lupus and how they may relate to clinical disease characteristics, variations, disparities and differences in response to therapies using functional genomic studies
Supporting documents for download
- Reference Table of Award Mechanisms – 23lrpreftable (1)
- Idea Award –HT9425-23-LRP-IA-GG
- Impact Award – HT9425-23-LRP-IPA-GG
- Transformative Vision Award –HT9425-23-LRP-TVA-GG
