Advancing Clinical Care Through Clinical Trials Award – HT9425-PRCRP-ACCCT
- up to USD$3M over 4 years
- Pre-applications due 25 May 2023
- Supports clinical trials that will progress to the next stage of study or improve the standard of care for individuals living with cancer.
- Requires a clinical trial to advance previously completed preclinical research to the clinic.
- preliminary data required
Career Development Award – Fellow Option – HT9425-PRCRP-CDA
- up to USD$400,000 over 3 years
- Pre-applications due 25 July 2023
- Supports independent, early-career investigators to conduct impactful research with the mentorship of an experienced cancer researcher.
- preliminary data required
- clinical trials not allowed
Patient Well-Being and Survivorship Award – HT9425-PRCRP-PWSA
- up to USD$1M over 4 years
- Pre-applications due 25 July 2023
- Supports innovative research studies to advance studies in preservation of function (physical ability), quality of life, symptom management, resilience, relief from neurocognitive deficits, and support for psychosocial issues related to cancer diagnosis, treatment, and survivorship.
- preliminary data required
- pilot clinical trials not allowed
Idea Award – HT9425-PRCRP-IA
- up to USD$400,000 over 2 years
- Pre-applications due 25 May 2023
- Supports innovative basic research that may introduce a new paradigm, challenge existing paradigms, look at existing problems from new perspectives, or exhibit other highly creative qualities.
- emphasis on innovation
- preliminary data required
- clinical trials not allowed
Impact Award – HT9425-PRCRP-IPA
- up to USD$1M over 3 years
- Pre-applications due 25 May 2023
- Supports hypothesis-driven, high-impact research.
- Supports mature research projects that specifically focus on critical scientific or clinical cancer issues and have the potential to make a major near-term impact
- preliminary data required
- clinical trials not allowed
Translational Team Science Award – HT9425-PRCRP-TTSA
- up to USD$2.5M over 4 years
- Pre-applications due 25 July 2023
- Emphasizes multi-PI, multidisciplinary collaborations.
- Supports advanced translational studies that are based on results from clinical investigations and to utilize information from the clinical trials for research that would then inform the clinic.
- preliminary data required
- clinical trials allowed
Proposals for all funding instruments must address at least 1 of each of the Topic Areas, Military Health Focus Areas and Overarching Challenges.
2023 Topic Areas
Bladder cancer; Blood cancers; Brain cancer; Colorectal cancer; Endometrial cancer; Esophageal cancer; Germ cell cancers; Head and Neck cancer; Liver cancer; Lymphoma; Mesothelioma; Metastatic cancers; Myeloma; Neuroblastoma; Pediatric, adolescent, and young adult cancers; Pediatric brain tumors; Stomach cancer; Sarcoma; Thyroid cancer; Von Hippel-Lindau syndrome malignancies (excluding cancers of the kidney and pancreas)
2023 Military Health Focus Areas
• Environmental exposure risk factors associated with cancer
• Mission Readiness and Gaps in Cancer Research
2023 Overarching Challenges
Prevention – Investigate innovative prevention strategies and early detection methods to decrease cancer burden; Elucidate the mechanisms underlying cancer development to improve prevention methods.
Diagnostics/Prognostics – Identify approaches to predict treatment resistance, recurrence, and the development of advanced disease; Distinguish unique features driving cancer occurrence across the spectrum of ages; Develop and improve minimally invasive methods to detect cancer initiation, progression, and recurrence.
Therapeutics – Transform cancer treatment, especially for advanced disease and metastasis; Improve current therapies, including systemic and local treatments; Research longitudinal evaluation of disease progression and/or treatment response; Elucidate the mechanisms of cancer development to improve treatment methods.
Patient Well-Being and Survivorship – Study methods to address survivorship issues, including quality of life, overall mental health, psychological impact of recurrence, and/or survivor permanent disability; Reduce short- and long-term treatment effects, including neurocognitive deficits; Investigate ways to bridge gaps between treatment and survivorship, including alternative medicine, nutrition and lifestyle factors, and supportive care.
Disparity – Improve prevention strategies, diagnosis, treatment, and outcomes for patients in underserved or under recognized populations; Study methods to improve accessibility to care and address survivorship; Advance health equity and reduce disparities in cancer care through research.
Supporting documents for download
