Pre-proposals due 24 May 2023
Clinical Trial Award – HT9425-23-SCIRP-CTA
- up to USD$3M over 4 years
- supports rapid implementation of clinical trials with potential to have significant impact on treatment or management of spinal cord injury
- projects may range from small proof-of-concept trials to demonstrate feasibility or inform the design of more advanced trails, through large-scale trials to determine efficacy in relevant populations
- applications are expected to name at least 2 community partners
- preliminary data required
Clinical Translation Research Award – HT9425-23-SCIRP-CTRA
- up to USD$1.25M over 3 years
- supports high-impact and/or new/emerging clinical research that may not be ready for a larger-scale clinical trial and for which feasibility/pilot studies are necessary.
- studies may be interventional or observational and may involve some
retrospective data analysis BUT purely retrospective or database-related research will not be supported - research may consist entirely of a small/pilot clinical trial.
- applications are expected to name at least 2 community partners
- preliminary data required
Translational Research Award – HT9425-23-SCIRP-TRA
- up to USD$1.25M over 3 years
- Funds studies that accelerate the movement of promising ideas in SCI research into clinical applications.
- May include a pilot clinical trial ONLY as a part of the proposed research where limited clinical testing of a novel intervention or device is necessary to inform the next step in the continuum of translational research.
- applications are expected to name at least 1 community partner
- preliminary data required
Investigator-Initiated Research Award – HT9425-23-SCIRP-IIRA
- up to USD$500,000 over 3 years
- Funds research that has the potential to make an important contribution to SCI research, patient care, and/or quality of life.
- Permitted research includes preclinical studies in animal models, research with human subjects, or human anatomical substances, as well as ancillary studies associated with an existing clinical trial.
- studies focused exclusively on target identification are discouraged
- clinical trials not allowed
- preliminary data required
2023 Focus Areas
- preserving & protecting spinal cord tissue at time of injury for improved neurologic outcomes
- identifying 7 validating biomarkers for diagnosis, prognosis and evaluation of treatment efficacies
- developing, testing, and validating promising interventions to address bowel, genitourinary, neuropathic pain, cardiopulmonary, or autonomic dysfunction in people with SCI
- investigating psychosocial issues relevant to people with SCI, their families, and/or their care partners
- rehabilitation and regeneration—maximizing the function of the residual neural circuitry, including harnessing neuroplasticity and recovery to improve function after SCI
Supporting documents for download
