Clinical Trial Award – HT9425-23-MSRP-CTA
- up to USD$1.6M over 3 years (FL1) or USD$4.5M over 4 years (FL2)
- preproposal due 8 June 2023
- FL1: Supports early-phase, proof-of-principle clinical trials to demonstrate feasibility or inform the design of more advanced trials, or other clinical trials
• FL2: Supports larger-scale clinical trials at phase 1 or 2 that seek to show preliminary evidence of safety or efficacy (benefit on clinical or paraclinical outcomes) in relevant patient populations.
• Scientific rationale and preliminary data required. - preclinical studies not allowed
- must address at least one of the following focus areas:
- Promoting Repair, Neuroprotection, and Remyelination in MS
- Treatment of MS Symptoms
Early Investigator Research Award – HT9425-23-MSRP-EIRA
- up to USD$320,000 over 2 years
- letter of intent due 24 July 2023
- must have 1 – 4 years continuous postdoctoral research experience
- Supports MS-focused research opportunities for individuals in the early stages of their careers.
- Investigator must have a designated mentor who is an experienced MS researcher.
- clinical trials not allowed
- must address at leasr one of the following focus areas:
- Central Nervous System Repair, Protection, and Regenerative Potential in MS
- Correlates of Disease Activity and Progression in MS
- Biology and Measurement of MS Symptoms
- Factors Contributing to or Associated with MS Etiology, Prodrome, Onset, and Disease Course
Exploration-Hypothesis Development Award – HT9425-23-MSRP-EHDA
- up to USD$250,000 over 2 years
- pre-applications due 8 June 2023
- Supports the initial exploration of innovative, high-risk, high-gain, and potentially groundbreaking concepts in the MS research field.
- New Investigator Option available
- preliminary data not required
- clinical trials not allowed
- must address one of the following focus areas:
- Central Nervous System Repair, Protection, and Regenerative Potential in MS
- Correlates of Disease Activity and Progression in MS
- Biology and Measurement of MS Symptoms
- Factors Contributing to or Associated with MS Etiology, Prodrome, Onset, and Disease Course
Investigator-Initiated Research Award – HT9425-23-MSRP-IIRA
- up to USD$1M over 3 years
- pre-applications due 8 June 2023
- Supports highly rigorous, high-impact research with the potential to make an important contribution to MS research and/or patient care. groundbreaking concepts in the MS research field.
- New Investigator Option available
- preliminary data required
- clinical trials not allowed
- must address one of the following focus areas:
- Central Nervous System Repair, Protection, and Regenerative Potential in MS
- Correlates of Disease Activity and Progression in MS
- Biology and Measurement of MS Symptoms
- Factors Contributing to or Associated with MS Etiology, Prodrome, Onset, and Disease Course
Supporting documents for download
- Reference table of award mechanisms – 23msrpreftable
- Clinical Trial Award – HT9425-23-MSRP-CTA-GG
- Early Investigator Research Award – HT9425-23-MSRP-EIRA-GG
- Exploration-Hypothesis Development Award –HT9425-23-MSRP-EHDA-GG
- Investigator-Initiated Research Award – HT9425-23-MSRP-IIRA-GG