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US Dept of Defense – Peer Reviewed Orthopaedic Research Program

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US Dept of Defense – Peer Reviewed Orthopaedic Research Program

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Applied Research Award  HT9425-PROP-ARA

  • up to USD$750,000 over 3 years
  • preproposal due 15 June 2023
  • Supports applied research applications focused on advancing optimal treatment and restoration of function for individuals with musculoskeletal injuries sustained during combat and service-related activities.
  • Proposed research should be supported by preliminary and/or published data and have the potential to advance toward clinical translation.
  • Funding must support preclinical applied research
  • clinical research and clinical trials not allowed
  • must address one of the following focus areas:
    • Limb Stabilization and Protection
    • Retention Strategies (battlefield care or return to duty)
    • Osseointegration
    • Composite Tissue Regeneration


Clinical Trial Award 
HT9425-PROP-CTA

  • up to USD$12.5M over 4 years (RL1) or USD$3M over 4 years (RL2)
  • preproposal due 15 June 2023
  • Supports rapid implementation of clinical
    trials with the potential to have a significant
    impact on treatment or management of
    military combat or service-related orthopaedic
    injuries that significantly impact unit
    readiness and return to duty/work rates.
  • must support a clinical trial
  • animal or preclinical research studies not allowed
  • must address one of the following focus areas:
    • Limb Stabilization and Protection
    • Retention Strategies (battlefield care or return to duty)
    • Translation of Early Findings (soft tissue trauma or fracture-related infection)
  • applications addressing Translation of Early Findings – Soft Tissue Trauma and include the Collaborative Care Option are eligible for RL2 funding

 

Clinical Translational Research Award HT9425-PROP-CTRA

  • up to USD$1.5M over 4 years
  • letters of intent due 15 June 2023
  • Supports high-impact and/or new/emerging clinical research that may not be ready for a full-scale randomized controlled clinical trial.
  • must support clinical research studies involving humans
  • preliminary data required
  • animal research not allowed
  • must address one of the following focus areas:
    • Retention Strategies (battlefield care or return to duty)
    • Volumetric Muscle Loss
    • Composite Tissue Regeneration
    • Osseointegration
    • Prostheses and Orthoses

 

Supporting documents for download

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