DARPA’s Defense Sciences Office will hold a webcast Information Session for the anticipated Selective Harnessing of Intrinsic Neuroplasticity Engineering (SHINIE) Disruption Opportunity 25 August 2026.
SHINE aims to harness neuroplasticity to precisely and non-invasively target and enhance the brain’s ability to adapt and rewire itself, allowing for more complete recovery after injury.
The program will establish whether adaptive neuroplasticity can be selectively induced within targeted, dysfunctional neural circuits while minimizing effects in surrounding tissue, enabling a new generation of precision neuroplasticity technologies. By fostering innovative approaches spanning molecular engineering, neuromodulation, biomaterials, behavioral interventions, and synthetic biology, SHINE aims to lay the scientific and technological foundation for future therapies capable of supporting the natural recovery and repair for dysfunctional neural circuits without disrupting healthy brain function.
Registration for webcast attendance closes 14 July 2026 or when capacity is reached.
Non-US citizens (academia and industry) must submit a DARPA Form 60 or an Official Visit Request (government personnel) by 14 July 2026.
DARPA Form 60’s are valid for 6 months from the date of issue. Holders of a valid form do not need to re-submit.
