US Dept of Defense – Parkinson’s Research Program

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Early Investigator Research Award – HT9425-23-PRP-EIRA

up to USD$500,000 over 2 years
letters of intent due 27 July 2023
postdoctoral, clinical fellows, assistant professors within 10 years of PhD or residency training
Supports research opportunities for investigators in the early stages of their careers, under the guidance of one or two designated Mentor(s).
Mentor(s) must have experience in Parkinson’s Disease research and mentoring
must address at least one of the FY23 Focus Areas
preliminary data encouraged but not required
clinical trials not allowed

Investigator-Initiated Research Award – HT9425-23-PRP-IIRA

up to USD$1.5M over 3 years
letters of intent due 27 July 2023
Supports highly rigorous, multidisciplinary, high- impact research projects that have the potential to make an important contribution to Parkinson’s research.
supports the full spectrum of research from basic science through clinical research.
must address at least one of the FY23 Focus Areas.
Preliminary data to support feasibility encouraged but not required
clinical trials allowed

Synergistic Idea Award – HT9425-23-PRP-SIA

up to USD$3M over 4 years
letters of intent due 27 July 2023
Supports new ideas that represent synergistic approaches to PD research involving two or four PIs.
Investigators should utilize their complementary and synergistic perspectives to address a central problem or question in Parkinson’s research.
designed to support both new and pre-existing partnerships and encourages participation of PIs from other research fields.
must address at least one of the FY23 Focus Areas.
Preliminary data to support feasibility encouraged but not required.
clinical trials allowed

23FY Focus Areas

Biological mechanisms or biomarkers, including biologically informed clinical evaluations, of non-motor symptoms that could lead to the development of treatments for PD. Applications focused on laboratory models through to human subjects, including computational approaches, would be considered. Examples of non-motor symptoms of interest include, but are not limited to:
- Cognitive dysfunction relevant to PD
- Psychiatric dysfunction
- Sleep and circadian rhythms disruptions
- Autonomic dysfunction
- Sensory dysfunction
- Other non-motor symptoms including fatigue, apathy, and impulse control disorders
Biological mechanisms or biomarkers associated with non-pharmacological interventions for PD. Examples of non-pharmacological interventions of interest include:
- Exercise
- Diet
- Neuro-stimulation therapy
- Neurosurgical